The Best Acne Product Deals You Can’t Miss During the Amazon Big Spring Sale— Prices as Low as $5

Shop Amazon Big Spring Sale Acne DealsE! Illustration; Photos Courtesy of Getty Images/ Tanja Ivanova

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The Amazon Big Spring Sale is the perfect opportunity to grab top acne treatments at unbeatable prices. With deals on products from trusted brands like Kate Somerville, Mario Badescu, Differin, Proactiv, Neutrogena, and Murad, you can finally tackle those breakouts and blemishes without breaking the bank.

Whether you’re looking for effective spot treatments, purifying masks, or gentle cleansers, this sale has something for every skincare need. Plus, with prices as low as $5, it’s never been easier to refresh your acne-fighting routine.

Don’t miss these amazing deals on must-have acne products and take advantage of the discounts while they last!

The Best Amazon Acne Product Deals

Terminator 10 Acne Spot Treatment with Benzoyl Peroxide

Say goodbye to stubborn breakouts with this powerful spot treatment that fights acne fast while soothing your skin.

$5.19$8Amazon

Neutrogena Stubborn Acne AM Treatment

Combat stubborn acne with this treatment that works to reduce breakouts and keep your skin clear and smooth throughout the day.

$9.48$17.39Amazon

PanOxyl Acne Treatment Bar

Fight acne with this effective benzoyl peroxide treatment bar that helps clear breakouts and keeps your skin looking smooth and blemish-free.

$7.69$15.99Amazon
E! Illustration; Photos Courtesy of Getty Images/ Olena Malik

Proactiv Skin Purifying Mask

Fight breakouts and refresh your skin with this purifying mask that deep-cleans pores, calms irritation, and helps prevent future acne flare-ups.

$28.99$40Amazon

CeraVe Resurfacing Retinol Serum

This retinol serum works wonders on acne marks by helping to fade discoloration and promote a smoother, more even skin tone.

$16.49$22Amazon

Vichy Normaderm PhytoAction Salicylic Acid Gel Cleanser

Clear your skin and tackle acne with this salicylic acid gel cleanser that helps remove excess oil, prevent breakouts, and leave your complexion feeling fresh and clean.

$16.09$22.99Amazon

Neutrogena Rapid Clear Stubborn Acne Spot Gel

Quickly clear up persistent acne with this effective spot treatment that targets breakouts and helps reduce redness for smoother, clearer skin.

$9.68$13.39Amazon
E! Illustration; Photos Courtesy of Getty Images/ angie marie photography

Daolyo Pimple Patches

Clear up acne quickly with these hydrocolloid pimple patches that absorb impurities, reduce blemishes, and work overnight with the power of salicylic acid, tea tree oil, and calendula.

$7.58$12.99Amazon

Proactiv Pore Cleansing Brush

Deeply cleanse and unclog pores with this charcoal-bristle brush that helps remove impurities and prevent acne breakouts for a smoother, clearer complexion.

$43$55Amazon

Differin Acne Retinoid Treatment Gel

Combat acne with this retinoid treatment that works deep within your skin to unclog pores, reduce breakouts, and improve your overall complexion.

$24.99$36..49Amazon
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Mario Badescu Drying Lotion

Lala Kent raved, “This is a game-changer. Just stick a qtip in there and dab it directly onto your pimple. I like to switch off between this and the pimple patches. I love this stuff. It’s the best.”

$12.60$18Amazon

Thayers Blemish Clearing Acne Pads

Target blemishes and soothe your skin with these gentle pads that help reduce irritation and redness.

$8.49$9.99Amazon

Grace & Stella Pimple Patches

Tackle breakouts effortlessly by using these pimple patches that help absorb impurities overnight.

$5$17Amazon

A313 French Pharmacy Vitamin A

I saw this trending on TikTok and had to try it. I’ve never used a retinol with this balm-like texture before—it’s such a unique experience. There’s a bit of a learning curve, but my skin is so clear and soft.

$33$44Amazon

Kate Somerville EradiKate Acne Treatment

Paige DeSorbo revealed, “This is my best kept secret. I’ve been using this Kate Somerville acne treatment for three years now. You take a Q-tip and you spot treatment your pimples. I love it.”

$23$28Amazon
E! Illustration; Photos Courtesy of Getty Images/ Iryna Veklich

Foreo Luna Mini 3- Premium Facial Cleansing Brush

Refresh your skin with this gentle yet effective facial cleansing device that leaves you with a smooth, glowing complexion.

$79$247Amazon

Murad Oil and Pore Control Mattifier Broad Spectrum SPF 45 PA++++

Control shine and protect your skin with a lightweight, oil-free moisturizer that keeps you matte and guarded with SPF 45.

$29.40$49Amazon

Elizabeth Arden Retinol + HPR Ceramide Capsules Rapid Skin Renewing Serum

Revitalize your skin day and night with these capsules, combining retinol and ceramides for smoother, more hydrated skin.

$39.20$56Amazon

Sunday Riley Good Genes Lactic Acid Treatment

“This really is so good. I only exfoliate once a week. This is an all-in-one lactic acid treatment. I’ve had it for 5 years. It’s the only exfoliant I use. I love that one,” Paige DeSorbo remarked.

$34.40$43Amazon
E! Illustration; Photos Courtesy of Getty Images/ Hispanolistic

How much is Amazon shipping?

Shipping costs on Amazon vary depending on the items ordered and delivery location. However, if you’re an Amazon Prime member, enjoy free and fast shipping on most items. Sign up now for a 30-day free trial to start saving on shipping.

How much is Amazon Prime Student membership?

Students can enjoy Amazon Prime at a discounted price of just $7.49 per month or $69 per year. Plus, sign up now and get a free 6-month trial to experience all the perks!

When is Amazon’s Big Spring Sale? 

The second annual Amazon Big Spring Sale runs from March 25 to March 31, 2025. Shoppers can score big discounts on beauty products, spring fashion, electronics, home essentials, and more.

What is on sale during the Amazon Big Spring Sale?

Shop exclusive deals on seasonal items like spring fashion, outdoor furniture, cleaning and organization products, and Amazon devices. Plus, enjoy limited-time lightning deals and daily discounts throughout the sale.

E! Illustration; Photos Courtesy of Getty Images/ Tanja Ivanova

How We Choose

The E! Insider Shop editors and writers search the internet to find the best products out there. We interview expert sources, comb through customer reviews, and use our own personal experiences to make shopping easier for our readers.

As an editorial team, we independently create content and determine coverage based on research, reporting and what we think our readers would like to read about. The goal of our content is to provide a service and inform readers who are on the hunt for the latest products to help make their life better. Items are sold by retailer, not E!. Pricing and availability are accurate as of publish time.

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